WebJunction Course Catalog

With a focus on a broad spectrum of illness biomarkers, Creative Biolabs has vast expertise developing diagnostic tests and assays for in vitro diagnostic (IVD) antibodies. In particular, we present leukemia biomarker development services and biomarker and antibody development.

Overview of Leukemia

A class of malignancies known as leukemia is characterized by elevated leucocyte counts in the bone marrow and/or blood. Acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML) are the four primary forms of leukemia. The leukemia cells are predominately present might be either mature, as in CLL, or precursor cells of different lineages, like in ALL and AML, or both, as in CML.  

Leukemia Diagnostic Instruments: Leukemia Biomarkers

Usually, aberrant results on a complete blood count are used to diagnose leukemia, which is then confirmed by looking at a blood film. A bone marrow aspirate and/or trephine biopsy that examines cell morphology and bone marrow architecture is typically used to confirm the diagnosis. Other methods that could be applied to further refine the leukemia type classification are genetic investigations and flow cytometric immunophenotyping. The diagnosis of leukemia depends heavily on genetic research, particularly when it comes to prognosis and treatment options. G-ban metaphase cytogenetics, fluorescence in situ hybridization (FISH), and in vitro molecular techniques (e.g., comparative genomic hybridization, SNP arrays, and PCR-based techniques) are often employed genetic approaches at leukemia diagnosis.